NFL schedule release: Bucs open title defense as 6-point favorite over Cowboys

The 2021 NFL schedule has been released, which means early point spreads and totals for games are out for the opening week of the season.

Here is the full list of lines for Week 1 games, courtesy of Caesars Sportsbook by William Hill. We will add more weeks as they get posted.

Note: These are opening lines, posted at 11:30 a.m. ET on Wednesday.

Thursday, Sept. 9

Dallas Cowboys at Tampa Bay Buccaneers (-6, 53)

Sunday, Sept. 12

1 p.m. games

Jacksonville Jaguars (-1.5, 46) at Houston Texans

Pittsburgh Steelers at Buffalo Bills (-6, 51)

New York Jets at Carolina Panthers (-4, 43.5)

Arizona Cardinals at Tennessee Titans (-2.5, 51.5)

Los Angeles Chargers (PK, 44.5) at Washington Football Team

Minnesota Vikings (-2.5, 47) at Cincinnati Bengals

San Francisco 49ers (-7.5, 47) at Detroit Lions

Philadelphia Eagles at Atlanta Falcons (-3.5, 47.5)

Seattle Seahawks at Indianapolis Colts (-2.5, 52)

4 p.m. games

Denver Broncos (-1, 43) at New York Giants

Green Bay Packers at New Orleans Saints (-1,5, 51)

Cleveland Browns at Kansas City Chiefs (-5.5, 53.5)

Miami Dolphins at New England Patriots (-1.5, 46)

8:20 p.m. game

Chicago Bears at Los Angeles Rams (-7, 45.5)

Monday, Sept. 13

Baltimore Ravens (-5.5, 51.5) at Las Vegas Raiders

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