Hollywood star George Clooney turns 60 years old today (May 6).
He made his acting debut on television back in 1978 and later gained wide recognition in his role as Dr Doug Ross on medical drama ER.
With 15 seasons spanning from 1994 until 2009, the Michael Crichton-created show was the second longest-running primetime medical drama in American TV history behind Grey's Anatomy.
The NBC series won 23 Primetime Emmy Awards, including the 1996 Outstanding Drama Series award, and received 124 Emmy nominations.
ER won 116 awards in total, including the Peabody Award, while the cast earned four Screen Actors Guild Awards for Outstanding Ensemble Performance in a Drama Series.
As of 2014, ER has grossed over $3billion in television revenue.
Most of the cast reunited last month on YouTube series Stars in the House in aid of clean bathe nonprofit Waterkeeper Alliance.
To mark George's birthday, and for 90s nostalgia, Daily Star has taken a look at what the stars of ER have been up too since leaving the show.
George Clooney – Dr Doug Ross
George rose to fame when he played Dr Doug Ross in ER from 1994 to 1999.
After leaving the series in 1999, he made a cameo appearance in the sixth season and returned for a guest spot in the show's final season.
For his work on the series, Clooney received two Primetime Emmy Award nominations for Outstanding Lead Actor in a Drama Series in 1995 and 1996.
Since leaving ER, George has gone on to appear in numerous Hollywood blockbusters including Ocean's Eleven and The Descendants.
He is also noted for his political and economic activism, and has served as one of the United Nations Messengers of Peace since 2008.
His love life has also hit the headlines over the years, but he's now married to legal barrister Amal, 43, and the pair are parent to twins Ella and Alexander
The father-of-two recently admitted that his two young children can speak Italian fluently despite being just three years old.
Julianna Margulies – Carol Hathaway
Julianna originally signed up as a guest star but ended up playing nurse Carol Hathaway in ER for six seasons.
The 54-year-old actress recently admitted to People that she and co-star George Clooney had a crush on one another while filming the show.
Carol and Doug's chemistry erupted on-screen and they turned into one of TV's hottest couples.
"That can't happen if you don't have a crush on each other," Julianna told the publication last month.
"And with George and me, it was so organic. I was just supposed to be a guest star, number 39 on the call sheet. But he treated everyone the same."
Since leaving her ER days behind, mother-of-one Julianna has appeared in The Good Wife, City Island, Dietland and Snakes on a Plane.
In 2015, Time magazine named her one of the 100 most influential people in the world.
The multi award-winning actress' memoir, Sunshine Girl: An Unexpected Life, comes out later this month.
Laura Innes – Dr Kerry Weaver
Actress Laura played Dr Kerry Weber, the skilled chief of the ER with an abrasive exterior and a physical disability, in the NBC medical drama from 1995 until 2007.
In 2006, the ER star told the Daily Mirror that 10 years of portraying Dr Weaver's limp had caused her to experience the early stages of actual spinal damage.
As as a result, producers introduced a plot arc in which Weaver's symptoms were surgically relieved.
She later reprised her role from 2008 until 2009 in the final season.
The award-winning TV star also directed a number of episodes of the series, and episodes of Brothers & Sisters, Studio 60 on the Sunset Strip, House and The West Wing.
Laura's first fiancé was reportedly murdered in the early 1980s.
She went on to marry amor David Brisbane and the pair are parents to son Cal and adopted daughter Mia.
The 63-year-old actress is an advocate for the disabled community, utilising her role as a director to help employ disabled people.
She is a supporter of the Performers with Disabilities Committee, which is associated with the Screen Actors Guild
Eriq La Salle – Dr Peter Benton
Dr Benton made his debut in the first-ever episode of ER back in 1994.
Eriq played the character for eight seasons but retuned for three episodes during its 15th and final season in 2009.
He published his first novel, Laws of Depravity, in 2012 and appeared in Under the Dome's third season in 2015.
In 2016, Eriq directed the episode Wingman in the Fox series Lucifer and the episode Black and Blue of TNT's Murder in the First.
He co-starred as Will Munson in the 2017 superhero film, Logan.
Eriq, now 58, has also directed and produced multiple episodes of Chicago PD throughout its six seasons.
Before appearing in ER, Eriq co-starred as Darryl Jenks in the Eddie Murphy movie Coming to America in 1988.
He reportedly didn’t reprise the role of Darryl in Coming 2 America in the 2021 sequel because he didn’t have the time while it was being made.
This was reported by TheGrio in 2019 after Eriq spoke with journalists during a press event.
Noah Wyle – Dr John Carter
Noah portrayed the role of John Carter in ER from 1994 until 2005.
He stated that he left the show because he wanted to spend more time with his family and friends and to make room for the upcoming generation.
However, in 2009, the actor returned to ER during its fifteenth and final season for five episodes, including the series finale.
After ER wrapped up, Noah capitalised on the show's success and starred in the Sci-Fi drama series Falling Skies, which aired for five seasons.
Noah became a spokesperson for the World Wide Fund for Nature (WWF) in 2009, claiming that polar bears are "hanging on by a thread" and "may be extinct in our children's lifetime, due to the effects of climate change".
In 2012, Noah and more than 100 members of the group ADAPT were arrested during a Capitol Hill protest to urge Congress not to cut Medicaid.
More recently, the TV star returned to somber ground with the crime drama series The Red Line, which explores some of America's harshest realities, a perfect vehicle for the actor to showcase his undeniable talent.
Noah, now 49, shares daughter Auden and son Owen with ex-wife Tracy Warbin, and daughter Frances Harper with wife Sara Wells.
Sherry Stringfield – Dr Susan Lewis
Actress Sherry is one of the original cast members of ER and she was nominated for an Emmy Award for lead actress during each of her first three seasons of the show.
However, a desire for a "normal life" prompted her to leave the drama in its third season.
She said at the time: "I wouldn't describe the situation as pleasant. The producers were in shock. They tried to talk me out of it. It took a long time to get out of my contract."
Susan Lewis' exit episode in November 1996 attracted 37million viewers, the biggest night of the season for the NBC network.
Following the birth of her daughter, Sherry approached the producers of ER and then rejoined the cast in 2001 for the show's eighth season.
Susan eventually checked out of the ER for good in 2005, at the beginning of Season 12, having been passed over for tenure in favour of John Carter by Kerry Weaver. She was offered a tenured position at a hospital in Iowa City.
Since leaving the medical drama, Sherry, now 53, has appeared in Criminal Minds spinoff, Criminal Minds: Beyond Borders as the wife of Gary Sinise's character, Jack Garrett.
As well as acting, Sherry has done voiceover work, including the voice of Eyeleen in the children's television show Blue's Clues and voicing her ER character for the PC game ER: The Game.
Anthony Edwards – Dr Mark Greene
Anthony's best known role is as Dr Mark Greene, which he played from the series premiere in 1994 until the end of the eight season in 2002.
His desire to pursue directing led to his request to be written out of the series.
The actor reportedly earned $35million for three seasons on ER, which made him one of television's highest-paid actors.
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In 2008, Anthony returned to ER to reprise his role as Dr Greene in flashback scenes, where he treats the dying son of character Catherine Banfield for one episode during its 15th and final season.
Following ER, he took some time off to raise his children. However, in 2013, he returned to episodic television with the conspiracy drama Zero Hour, playing the male lead Hank Galliston.
The TV star was also the voice of Echo, one of the fighter jets, in the Disneytoon Studios film Planes, and also voiced the character Pegleg Pirate in an episode of Blaze and the Monster Machines.
Anthony, who has been a licensed private pilot since 2012, served as the director of the 2016 film My Dead Boyfriend.
In 2018, Anthony, now 58, was cast in the recurring role in the third season of Netflix's Designated Survivor as Mars Harper, the President's Chief of Staff.
Parminder Nagra – Dr Neela Rasgotra
Parminder played Dr Neela Rasgotra in ER from 2003 until 2009.
Before joining the cast of the medical drama, she made a name for herself playing Jess Bhamra in 2002 movie Bend It Like Beckham.
Since appearing in the US series, the actress has appeared in several movies such as Twenty8k, Bird Box and Five Feet Apart.
She was one of the bearers of the Olympic torch as it passed through London on its way to the 2004 Summer Olympics in Athens, Greece.
Parminder married photographer James Stenson in 2009 and her ER co-star Scott Grimes and John Stamos performed at the ceremony and Maura Tierney Maura officiated.
In 2009, she gave birth to their son Kai David Singh Stenson and it was reported that Nagra had filed for divorce in 2012. The divorce was finalised in 2013.
The TV star recently revealed that she was once turned down for a role on a well-known US TV show because they "already had an Indian person".
She told the Celebrity Catch Up podcast she had also heard producers on an unnamed production say "too many brown people" would not sell.
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