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New coronavirus vaccine test results have been hailed as a "critical milestone" by the chief behind the drug.
Pharmaceutical company Pfizer has announced its coronavirus vaccine candidate is more than 90% effective in preventing Covid-19 during a major trial.
Labour leader Sir Keir Starmer has described the breakthrough as encouraging.
He tweeted. "This is really encouraging news."
Prime Minister Boris Johnson will make an announcement from Downing Street following the news.
Pfizer, which is developing the mRNA-based vaccine with BioNTech, said the results were from an independent interim analysis of the results of its phase three clinical study.
Dr Albert Bourla, Pfizer chairman and CEO, said: "Today is a great day for science and humanity.
"The first set of results from our phase three Covid-19 vaccine trial provides the initial evidence of our vaccine's ability to prevent Covid-19.
"We are reaching this critical milestone in our vaccine development programme at a time when the world needs it most.
"With today's news, we are a significant step closer to providing people around the world with a much-needed breakthrough to help bring an end to this global health crisis.
Ian Jones, professor of virology at the University of Reading, said the Pfizer trial data shows "really impressive protection and no reported adverse events".
He said: "Of all the current vaccines currently in development the BioNtech product always looked like the most bang-per-buck as it is entirely focused on the part of the virus that binds to the human cell, the receptor binding domain.
"The only things we will not know for some time is the longevity of the response in all age groups, but assuming antibody titres are high that should be at least as good as any other vaccine currently in trial."
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